| No | Size | Price | Availability | |
| ARP9531-61 | 50ul | 1500.00 | In Stock |  |
| ARP9531-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9531 |
| Isotype: | IgG | Swiss Prot: | O95817 |
| purity: | Affinity purification |
| Background: |
| BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 62 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | BAG-3, BAG-family molecular chaperone regulator-3, BCL-2 binding athanogene- 3, Bcl-2-binding protein Bis, BIS, Docking protein CAIR-1 |
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