Source: | Rabbit | Gene Id: | 55743 |
Isotype: | IgG | Swiss Prot: | Q96EP1 |
purity: | Affinity purification |
Background: |
This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Mar 2014] |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 73 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | checkpoint with forkhead and ring finger domains, Checkpoint with forkhead and RING finger domains protein, CHFR, E3 ubiquitin-protein ligase CHFR, FLJ10796, FLJ33629, RING finger protein 196, RNF116, RNF196 |
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