ANAPC5 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP51433-61 50ul 1500.00 In Stock
ARP51433-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 51433
Isotype: IgG Swiss Prot: Q9UJX4
purity: Affinity purification
Background:
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 85 kDa
Recommended Dilutions
WB 1:500-1:1000
Immunogen A synthetic peptide
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym ANAPC5, Anaphase-promoting complex subunit 5, ANC5, Similar to anaphase-promoting complex subunit 5
This product is for research use only, not for diagnostic or therapeutic use!

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