ANAPC5 Rabbit Polyclonal Antibody
No |
Size |
Price |
Availability |
|
ARP51433-61 |
50ul |
1500.00 |
In Stock |
 |
ARP51433-61 |
100ul |
2000.00 |
In Stock |
 |
Source: |
Rabbit |
Gene Id: |
51433 |
Isotype: |
IgG |
Swiss Prot: |
Q9UJX4 |
purity: |
Affinity purification |
Background: |
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq |
Reactivity |
Human |
Tested applications |
WB |
Clonality |
Polyclonal Antibody |
Calculated MW |
85 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen |
A synthetic peptide |
Storage |
Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym |
ANAPC5, Anaphase-promoting complex subunit 5, ANC5, Similar to anaphase-promoting complex subunit 5 |
This product is for research use only, not for diagnostic or therapeutic use!