Source: | Rabbit | Gene Id: | 9442 |
Isotype: | IgG | Swiss Prot: | Q6P2C8 |
purity: | Affinity purification |
Background: |
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 35 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Cofactor required for Sp1 transcriptional activation subunit 8, cofactor required for Sp1 transcriptional activation, subunit 8 (34kD), cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa, CRAP34, CRSP complex subunit 8, CRSP34, CRSP8 |
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