| No | Size | Price | Availability | |
| ARP5887-62 | 50ul | 1500.00 | In Stock |  |
| ARP5887-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5887 |
| Isotype: | IgG | Swiss Prot: | P54727 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 50 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | UV excision repair protein RAD23 homolog B, hHR23B, XP-C repair-complementing complex 58 kDa protein, p58, RAD23B |
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