| No | Size | Price | Availability | |
| ARP525-61 | 50ul | 1500.00 | In Stock |  |
| ARP525-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 525 |
| Isotype: | IgG | Swiss Prot: | P15313 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 60 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Vacuolar ATP synthase subunit B, kidney isoform, V-ATPase subunit B 1, Vacuolar proton pump subunit B 1, Endomembrane proton pump 58 kDa subunit, ATP6V1B1, ATP6B1, VATB, VPP3 |
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