Source: | Rabbit | Gene Id: | 8891 |
Isotype: | IgG | Swiss Prot: | Q9NR50 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 50 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EI2BG, EIF-2B, eIF-2B GDP-GTP exchange factor subunit gamma, EIF2B3, EIF2Bgamma, eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa, Translation initiation factor eIF-2B subunit gamma |
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