| No | Size | Price | Availability | |
| ARP22941-61 | 50ul | 1500.00 | In Stock |  |
| ARP22941-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 22941 |
| Isotype: | IgG | Swiss Prot: | Q9UPX8 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 135 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | cortactin binding protein 1, cortactin SH3 domain-binding protein, CORTBP1, CTTNBP1, GKAP/SAPAP interacting protein, ProSAP1, SH3 and multiple ankyrin repeat domains 2, SHAN2, SHANK, SPANK-3 |
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