Source: | Rabbit | Gene Id: | 5519 |
Isotype: | IgG | Swiss Prot: | P30154 |
purity: | Affinity purification |
Background: |
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 66 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | 2AAB, beta isoform of regulatory subunit A, protein phosphatase 2, PP2A, A, PR65-beta isoform, PP2A, A, R1-beta isoform, PR65B, protein phosphatase 2 (formerly 2A), regulatory A (PR 65), beta isoform, protein phosphatase 2 (formerly 2A), regulatory A, bet |
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