| No | Size | Price | Availability | |
| ARP6001-61 | 50ul | 1500.00 | In Stock |  |
| ARP6001-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6001 |
| Isotype: | IgG | Swiss Prot: | O43665 |
| purity: | Affinity purification |
| Background: |
| Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 20 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Regulator of G-protein signaling 10, RGS10 |
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