| No | Size | Price | Availability | |
| ARP5091-61 | 50ul | 1500.00 | In Stock |  |
| ARP5091-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5091 |
| Isotype: | IgG | Swiss Prot: | P11498 |
| purity: | Affinity purification |
| Background: |
| This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 120 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | EC 6.4.1.1, PCB, PYC, Pyruvate carboxylase, mitochondrial, Pyruvic carboxylase |
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