Source: | Rabbit | Gene Id: | 9369 |
Isotype: | IgG | Swiss Prot: | Q9HDB5 |
purity: | Affinity purification |
Background: |
Neurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules and receptors. They are encoded by several unlinked genes of which two, NRXN1 and NRXN3, are among the largest known human genes. Three of the genes (NRXN1-3) utilize two alternate promoters and include numerous alternatively spliced exons to generate thousands of distinct mRNA transcripts and protein isoforms. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms; a much smaller number of transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. [provided by RefSeq |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 70 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Na(+)/H(+) exchange regulatory cofactor NHE-RF2, NHERF-2,NHE3 kinase A regulatory protein E3KARP, SRY-interacting protein 1, SIP-1, Sodium-hydrogen exchanger regulatory factor 2,Solute carrier family 9 isoform A3 regulatory factor 2, Tyrosine kinase activ |
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