| No | Size | Price | Availability | |
| ARP8720-61 | 50ul | 1500.00 | In Stock |  |
| ARP8720-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8720 |
| Isotype: | IgG | Swiss Prot: | Q14703 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014] |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 118 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Endopeptidase S1P, KIAA0091, MBTP1, MBTPS1, membrane-bound transcription factor peptidase, site 1, membrane-bound transcription factor protease, site 1, Membrane-bound transcription factor site-1 protease, MGC138711, MGC138712, PCSK8, S1P, site-1 protease |
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