Source: | Rabbit | Gene Id: | 7264 |
Isotype: | IgG | Swiss Prot: | Q13630 |
purity: | Affinity purification |
Background: |
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 40 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | GDP-L-fucose synthetase, EC 1.1.1.271, Protein FX, Red cell NADP(H)-binding protein, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase |
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