| No | Size | Price | Availability | |
| ARP149461-61 | 50ul | 1500.00 | In Stock |  |
| ARP149461-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 149461 |
| Isotype: | IgG | Swiss Prot: | Q8N6F1 |
| purity: | Affinity purification |
| Background: |
| The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq |
| Reactivity | Human, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 23 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | claudin-19, CLD19, CLDN19 |
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