Source: | Rabbit | Gene Id: | 1259 |
Isotype: | IgG | Swiss Prot: | P29973 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 79 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | cGMP-gated cation channel alpha 1, CNCG, CNCG1, CNG channel alpha 1, CNG-1, CNG1, Cyclic nucleotide gated channel alpha 1, Cyclic nucleotide gated channel, photoreceptor, Cyclic-nucleotide-gated cation channel 1, Rod photoreceptor cGMP-gated channel alpha |
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