
| Source: | Rabbit | Gene Id: | 1369 |
| Isotype: | IgG | Swiss Prot: | P15169 |
| purity: | Affinity purification |
| Background: |
| Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 52 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | anaphylatoxin inactivator, arginine carboxypeptidase, carboxypeptidase N 1, carboxypeptidase N catalytic, carboxypeptidase N polypeptide 1 50 kD, carboxypeptidase N small subunit, CBPN, CPN, EC 3.4.17.3, kininase-1, lysine carboxypeptidase, plasma carboxy |
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