Source: | Rabbit | Gene Id: | 11238 |
Isotype: | IgG | Swiss Prot: | Q9Y2D0 |
purity: | Affinity purification |
Background: |
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 38 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Carbonic anhydrase 5B, mitochondrial [Precursor], EC 4.2.1.1, Carbonic anhydrase VB, CA-VB, Carbonate dehydratase VB, CA5B |
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