TAS2R16 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP11621-01 50ul 1500.00 In Stock
YRP11621-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id:
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
T2R16 is a 291 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. Acting in the oral cavity and the gastrointestinal tract, T2R16 is a gustducin-coupled receptor that is implicated in the perception of bitter compounds. T2R16 mediates responses to certain taste through PLC ∫2, a phospholipase C selectively expressed in taste tissue, and the calcium-regulated cation channel TRPM5. Expressed in a subset of gustducin-positive taste receptor cells of the tongue and epithelia, T2R16 confers bitter perception of salicin to non-taster mice. The gene that encodes T2R16 consists of 996 bases and maps to human chromosome 7q31. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The Lys-172 polymorphism in T2R16 is associated with genetic susceptibility to alcoholism.
Reactivity Human
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human TAS2R16
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym TAS2R-16, T2R16, Taste receptor type 2 member 16, T2R16_HUMAN.
This product is for research use only, not for diagnostic or therapeutic use!

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