| No | Size | Price | Availability | |
| ARP1244-61 | 50ul | 1500.00 | In Stock |  |
| ARP1244-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1244 |
| Isotype: | IgG | Swiss Prot: | Q92887 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 174 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Canalicular multispecific organic anion transporter 1,ATP-binding cassette sub-family C member 2,Canalicular multidrug resistance protein,Multidrug resistance-associated protein 2 ,ABCC2 ,CMOAT, CMOAT1, CMRP, MRP2 |
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