Source: | Rabbit | Gene Id: | 63941 |
Isotype: | IgG | Swiss Prot: | Q96P71 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Reactivity | Human, Mouse |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 44 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | AB2BP, amyloid beta A4 protein-binding family A member 2-binding, APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, N-terminal EF-hand calcium binding 3, NECA3, NECAB 3, Nek2-interacting 1, neuronal calcium-binding 3, NIP1, STIP3, SYTIP2, X11L-binding 51, XB51 |
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