Source: | Rabbit | Gene Id: | 80270 |
Isotype: | IgG | Swiss Prot: | Q9H2F3 |
purity: | Affinity purification |
Background: |
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 41 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | 3 beta-hydroxysteroid dehydrogenase type 7, 3 beta-hydroxysteroid dehydrogenase type VII, 3-beta-HSD VII, 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase, 3BHS7, EC 1.1.1.-, HSD3B7 |
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