| No | Size | Price | Availability | |
| ARP5718-61 | 50ul | 1500.00 | In Stock |  |
| ARP5718-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5718 |
| Isotype: | IgG | Swiss Prot: | O00232 |
| purity: | Affinity purification |
| Background: |
| The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 50 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | 26S proteasome non-ATPase regulatory 12, 26S proteasome regulatory p55, proteasome (prosome, macropain) 26S, non-ATPase, 12, proteasome 26S non-ATPase 12, proteasome 26S non-ATPase 12 isoform 1 variant, PSD12 |
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