| No | Size | Price | Availability | |
| ARP27030-61 | 50ul | 1500.00 | In Stock |  |
| ARP27030-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 27030 |
| Isotype: | IgG | Swiss Prot: | Q9UHC1 |
| purity: | Affinity purification |
| Background: |
| This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 164 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DNA mismatch repair protein Mlh3, MutL protein homolog 3 |
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