Source: | Rabbit | Gene Id: | 1558 |
Isotype: | IgG | Swiss Prot: | P10632 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq |
Reactivity | Human |
Tested applications | IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 56 kDa |
Recommended Dilutions |
IHC 1:50-1:200
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Cytochrome P450 2C8, EC 1.14.14.1, CYPIIC8, P450 form 1, P450 MP-12/MP-20, P450 IIC2, S-mephenytoin 4-hydroxylase, CYP2C8, CP2C8 |
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