Source: | Rabbit | Gene Id: | 1006 |
Isotype: | IgG | Swiss Prot: | P55286 |
purity: | Affinity purification |
Background: |
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008] |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 90 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Cadherin-8 [Precursor], CDH8, CADH8 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.