Source: | Rabbit | Gene Id: | 8539 |
Isotype: | IgG | Swiss Prot: | Q9BZZ5 |
purity: | Affinity purification |
Background: |
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 58 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | AAC-11, API-5, API5-like 1, API5L1, FIF, XAGL protein, apoptosis inhibitor 5, fibroblast growth factor 2-interacting factor, fibroblast growth factor 2-interacting factor 2, migration-inducing protein MIG8 |
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