
| Source: | Rabbit | Gene Id: | 11213 |
| Isotype: | IgG | Swiss Prot: | Q9Y616 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. |
| Reactivity | Human |
| Tested applications | WB IHC IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 68 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Interleukin-1 receptor-associated kinase 3, EC 2.7.11.1, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M, IRAK3 |
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