Source: | Rabbit | Gene Id: | 23192 |
Isotype: | IgG | Swiss Prot: | Q9Y4P1 |
purity: | Affinity purification |
Background: |
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Two transcript variants that encode different isoforms were identified through sequence analysis. |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 44 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Cysteine protease ATG4B, EC 3.4.22.-, Autophagy-related protein 4 homolog B, hAPG4B, Autophagin-1, Autophagy-related cysteine endopeptidase 1, AUT-like 1 cysteine endopeptidase, ATG4B, APG4B, AUTL1, KIAA0943 |
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