| No | Size | Price | Availability | |
| ARP22806-61 | 50ul | 1500.00 | In Stock |  |
| ARP22806-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 22806 |
| Isotype: | IgG | Swiss Prot: | Q9UKT9 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. [provided by RefSeq |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 62 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | AIOL, IKZF3, ZNFN1A3, zinc finger protein Aiolos |
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