| No | Size | Price | Availability | |
| ARP9451-61 | 50ul | 1500.00 | In Stock |  |
| ARP9451-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9451 |
| Isotype: | IgG | Swiss Prot: | Q9NZJ5 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
| Reactivity | Human |
| Tested applications | WB IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 125 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | E2AK3, EC 2.7.11.1, EIF2AK3, Eukaryotic translation initiation factor 2-alpha kinase 3 precursor, HsPEK, PEK, PERK, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, kinase PERK |
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