Source: | Rabbit | Gene Id: | 51776 |
Isotype: | IgG | Swiss Prot: | Q9NYL2 |
purity: | Affinity purification |
Background: |
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq |
Reactivity | Human, Mouse |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 91 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | AZK, EC 2.7.11.25, MLTK, MRK-beta, mixed lineage kinase-related kinase, sterile alpha motif and leucine zipper containing kinase AZK |
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