
| Source: | Rabbit | Gene Id: | 8569 |
| Isotype: | IgG | Swiss Prot: | Q9BUB5 |
| purity: | Affinity purification |
| Background: |
| Mnk1 a CAM kinase of the MAPKKAPK family that can regulate translation. Following activation by MAP kinases, Mnk1 phosphorylates eIF4E at Ser209, increasing its affinity for the 7-methylguanosine-containing mRNA cap. Two MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for its kinase activity. Three alternatively spliced human isoforms have been described. |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 51 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | MAP kinase-interacting serine/threonine-protein kinase 1, EC 2.7.11.1, MAP kinase signal-integrating kinase 1, Mnk1, MKNK1, MNK1 |
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