| No | Size | Price | Availability | |
| ARP1852-61 | 50ul | 1500.00 | In Stock |  |
| ARP1852-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1852 |
| Isotype: | IgG | Swiss Prot: | Q99956 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 42 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Dual specificity protein phosphatase 9, EC 3.1.3.48, EC 3.1.3.16, Mitogen-activated protein kinase phosphatase 4, MAP kinase phosphatase 4, MKP-4, DUSP9, MKP4 |
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