Source: | Rabbit | Gene Id: | 142679 |
Isotype: | IgG | Swiss Prot: | Q8WTR2 |
purity: | Affinity purification |
Background: |
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] |
Reactivity | Human |
Tested applications | WB IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 28 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Dual specificity protein phosphatase 19, EC 3.1.3.48, EC 3.1.3.16, Stress-activated protein kinase pathway-regulating phosphatase 1, Protein phosphatase SKRP1, Dual-specificity phosphatase TS-DSP1, LMW-DSP3, DUSP19, DUSP17, SKRP1 |
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