| No | Size | Price | Availability | |
| ARP22853-61 | 50ul | 1500.00 | In Stock |  |
| ARP22853-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 22853 |
| Isotype: | IgG | Swiss Prot: | Q8IWU2 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009] |
| Reactivity | Human |
| Tested applications | WB IHC IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 164 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | 2900041G10Rik, BREK, cprk, EC 2.7.11.1, KIAA1079, kinase LMR2, kinase phosphatase inhibitor 2, KPI-2, lemur tyrosine kinase 2, LMTK2 |
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