| No | Size | Price | Availability | |
| ARP283455-62 | 50ul | 1500.00 | In Stock |  |
| ARP283455-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 283455 |
| Isotype: | IgG | Swiss Prot: | Q6VAB6 |
| purity: | Affinity purification |
| Background: |
| KSR2 Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF. 2 isoforms of the human protein are produced by alternative splicing. |
| Reactivity | Human, Mouse |
| Tested applications | WB IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 108 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | hKSR2, Kinase suppressor of Ras 2, KSR2 |
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