STEA3 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP55240-62 50ul 1500.00 In Stock
ARP55240-62 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 55240
Isotype: IgG Swiss Prot: Q658P3
purity: Affinity purification
Background:
STEAP3 a multi-pass membrane protein induced directly by p53. Plays an important role in facilitating exosome secretion. Enhances secretion in the DNA damage-induced p53-dependent exosomal secretory pathway. Localizes to vesicular-like structures at the plasma membrane and around the nucleus. Highly expressed in hematopoietic tissues where it localizes to the specialized endosome. An endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor.
Reactivity Human, Mouse, Rat
Tested applications WB IF ICC
Clonality Polyclonal Antibody
Calculated MW 54 kDa
Recommended Dilutions
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
Immunogen A synthetic peptide
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym Metalloreductase STEAP3, EC 1.16.1.-, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, hTSAP6, pHyde, hpHyde, Dudulin-2, STEAP3, TSAP6
This product is for research use only, not for diagnostic or therapeutic use!

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