| No | Size | Price | Availability | |
| ARP5469-62 | 50ul | 1500.00 | In Stock |  |
| ARP5469-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5469 |
| Isotype: | IgG | Swiss Prot: | Q15648 |
| purity: | Affinity purification |
| Background: |
| The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008] |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 170 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Mediator complex subunit 1 |
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