Source: | Rabbit | Gene Id: | 23542 |
Isotype: | IgG | Swiss Prot: | Q13387 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 87 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | C-jun-amino-terminal kinase-interacting protein 2, JNK-interacting protein 2, JIP-2, JNK MAP kinase scaffold protein 2, Islet-brain-2, IB-2, Mitogen-activated protein kinase 8-interacting protein 2, MAPK8IP2, IB2, JIP2, PRKM8IPL |
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