| No | Size | Price | Availability | |
| ARP6764-61 | 50ul | 1500.00 | In Stock |  |
| ARP6764-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6764 |
| Isotype: | IgG | Swiss Prot: | P78524 |
| purity: | Affinity purification |
| Background: |
| This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 126 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Suppression of tumorigenicity 5, HeLa tumor suppression 1, DENN domain-containing protein 2B, ST5, DENND2B, HTS1 |
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