| No | Size | Price | Availability | |
| ARP2073-61 | 50ul | 1500.00 | In Stock |  |
| ARP2073-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2073 |
| Isotype: | IgG | Swiss Prot: | P28715 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011] |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 130 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DNA excision repair protein ERCC-5, DNA-repair protein complementing XP-G cells, ERCC5, XPGC, Xeroderma pigmentosum group G complementing protein |
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