Source: | Rabbit | Gene Id: | 4800 |
Isotype: | IgG | Swiss Prot: | P23511 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 43 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CAAT-box DNA binding protein subunit A, CBF-A, CBF-B, CCAAT-binding transcription factor subunit B, HAP2, HAP2 CCAAT-binding protein, NF-Y protein chain A, NFYA, nuclear transcription factor Y, alpha, transcription factor NF-Y, A subunit |
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