KAP2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5576-61 50ul 1500.00 In Stock
ARP5576-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5576
Isotype: IgG Swiss Prot: P13861
purity: Affinity purification
Background:
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 45 kDa
Recommended Dilutions
WB 1:500-1:1000
Immunogen A synthetic peptide
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym KAP2, MGC3606, PKR2, PRKAR2
This product is for research use only, not for diagnostic or therapeutic use!

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