| No | Size | Price | Availability | |
| ARP3074-61 | 50ul | 1500.00 | In Stock |  |
| ARP3074-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3074 |
| Isotype: | IgG | Swiss Prot: | P07686 |
| purity: | Affinity purification |
| Background: |
| Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 63 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Beta-hexosaminidase beta chain [Precursor], EC 3.2.1.52, N-acetyl-beta-glucosaminidase, Beta-N-acetylhexosaminidase, Hexosaminidase B, Cervical cancer proto-oncogene 7 protein, HCC-7, Beta-hexosaminidase beta-B chain, Beta-hexosaminidase beta-A chain, HEX |
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