| No | Size | Price | Availability | |
| ARP86-61 | 50ul | 1500.00 | In Stock |  |
| ARP86-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 86 |
| Isotype: | IgG | Swiss Prot: | O96019 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 47 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human ACTL6A |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ACTL6, ACTL6A, MGC5382, actin-like 6A |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
