| No | Size | Price | Availability | |
| YRP00186-01 | 50ul | 1500.00 | In Stock |  |
| YRP00186-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 18389 |
| Isotype: | IgG | Swiss Prot: | P35377 |
| purity: | Purified by Protein A. |
| Background: |
| G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from mouse Nociceptin receptor |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | KOR3, ORGC, ORL1, Oprl, XOR1, morc, KOR-3, LC132, MOR-C, Nociceptin receptor, K3 opiate receptor, Kappa-type 3 opioid receptor, Orphanin FQ receptor, Oprl1, Oor |
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