| No | Size | Price | Availability | |
| ARP983P-62 | 50ul | 1500.00 | In Stock |  |
| ARP983P-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 983 |
| Isotype: | IgG | Swiss Prot: | P06493 |
| purity: | Affinity purification |
| Background: |
| Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1, B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 34 kDa |
| Recommended Dilutions |
WB 0.736111
IHC 1:50-1:200
|
| Immunogen | A synthetic phosphopeptide derived from human CDC2 around the phosphorylation site of Threonine161 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CDC28, CDC2A, CDK1, Cell division control protein 2 homolog, Cyclin-dependent kinase 1, EC 2.7.11.22, EC 2.7.11.23, MPF, kinase Cdc2, p34 protein kinase |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
