| No | Size | Price | Availability | |
| ARP6093-61 | 50ul | 1500.00 | In Stock |  |
| ARP6093-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6093 |
| Isotype: | IgG | Swiss Prot: | Q13464 |
| purity: | Affinity purification |
| Background: |
| ROCK1 Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 160 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A synthetic peptide derived from human ROCK1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | MGC131603, MGC43611, p160 ROCK-1, p160-ROCK, p160ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, Rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase |
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