Source: | Rabbit | Gene Id: | 2534 |
Isotype: | IgG | Swiss Prot: | P06241 |
purity: | Affinity purification |
Background: |
FANCD2 Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 60 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human Fyn |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | DKFZp762A223, FA-D2, FA4, FACD, FACD2, FAD, FAD2, FANCD, FANCD2, Fanconi anemia group D2 protein, Fanconi anemia, complementation group D2, FLJ23826, Protein FACD2, type 4 Fanconi pancytopenia |
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